|Education: Theory & Practice:|
|K. Shukri, S. Velikova, E. Mehmed|
Health and Environment [In Bulgarian]
Looking for Talanted and Gifted Pupils [In Bulgarian]
Full text: PDF (399 K)
|A. Pashov, S. Yordanova-Dyulgerova, B. Karaivanova-Dolchnkova, R. Draganova-Hristova|
The Seminar - Practicum in Non-Formal Learning - Oppotunities and Developing Skills and Creativity THrough the Prism of Physics [In Bulgarian]
Full text: PDF (393 K)
Learning Community of Teachers [In Bulgarian]
Full text: PDF (401 K)
|R. Rangelova, M. Mavrova|
Physics, Man and Nature, and Pupils in Our Days [In Bulgarian]
Full text: PDF (288 K)
Determination of Earth Acceleration: An Experimental Task [In Bulgarian]
Full text: PDF (686 K)
|K. Katsarova, Z. Raykova|
Model Study of the Mechanical Oscillations and Waves in High School (9th Grade) by Applying the Teaching Research Approach [In Bulgarian]
Full text: PDF (362 K)
|D. Uzunova, B. Velkovski, I. Simeonov, V. Shabanski, D. Kolev|
Robotics for the Beginners [In Bulgarian]
Full text: PDF (999 K)
The Discipline "The Origin of Life and Theories of Evolution" in the Professional Training of the Biology Teacher [In Bulgarian]
Full text: PDF (425 K)
|From the Research Laboratories:|
|R. Georgiev, T. Dzimbova, A. Chapkanov|
Design and Docking Studies of His-Leu Analogues as Potential ACE Inhibitors
Full text: PDF (1076 K)
|K. T. Rustembekov, M. Stoev, A. A. Toibek|
X-Ray Diffraction Study of M2Zn(TeO3)2 (M - Na,K) Telluride
Full text: PDF (814 K)
|A. Vasev, P. Lilov, G. Ivanova, Y. Marinov, A. Stoyanova, V. Mikli, A. Stoyanova - Ivanova|
Electrochemical Impedance Study of BSCCO (2212) Cuprate Ceramic Additive to the Zink Electrode in Ni-Zn Batteries
Full text: PDF (1343 K)
|N. Dineva, I. Givechev, D. Tanev, D. Danalev|
Calibration of GC/MS Method for Determination of Phthalates
Full text: PDF (912 K)
|M. Chochkova, B. Stoykova, I. Romanova, P. Petrova, I. Tsvetkova, H. Najdenski, L. Nikolaeva - Glomb, N. Nikolova, G. Ivanova, A. Chapkanov, T. Milkova, M. Sticha, I. Nemec|
Sonochemical Synthesis of 4-Aminoantipyrine Schiff Bases and Evaluation of Their Antimicrobial, Anti-Tyrosinase and DPPH Scaverging Activties
Full text: PDF (939 K)
|S.S. Fomanyuk, V.O. Smilyk, G.Y. Kolbasov, L.A. Rusetsky, T.A. Mirnaya|
Electrosynthesis of Cadmium Selenide Nanoparticles with Simultaneous Extraction into P-Xylene
Full text: PDF (484 K)
|H.M.E. Madkour, O.E.A. Mostafa, E.A. El-Bardany, A.K. El-Ziaty, M. Nabil|
Synthesis and Characterization of Novel Heterocycles with Anticipated Antimicrobial Activities from Pyranopyrazole Derivative
Full text: PDF (418 K)
|M. Filipova, D. Popova, S. Vezenkov|
Biological Aspect of Recanalization with Venous Thrombolysis [In Bulgarian]
Full text: PDF (246 K)
Khimiya, Volume 27, Issue 6(2018)
Khimiya. 27, 799-810 (2018) Author(s): K. Shukri, S. Velikova, E. Mehmed:
Abstract.The effect of the environment on the human health is discussed in brief. Examples of using medical plants and dietary foods to improve a human health are given.
Keywords: health, foods, sun rays, nature, environment
Khimiya. 27, 811-815 (2018) Author(s): Z. Kyurkchieva:
Abstract.In this article, the author shares the experience of searching, finding and working with talented and gifted students. The descriptions have been applied at the National Lyceum “Professor Lyubomir Tchakalov” in Sofia.
Keywords: talented pupils, gifted pupils, science in high school
Khimiya. 27, 816-824 (2018) Author(s): A. Pashov, S. Yordanova-Dyulgerova, B. Karaivanova-Dolchnkova, R. Draganova-Hristova:
Abstract.The report presents a seminar-practicum, including theory, observation and experimental activity, applicable to teaching Physics and astronomy in Grade 7. Through separate work centers, under the leadership of lecturers and students from Sofia University “St. Kliment Ohridski” experimental tasks, such as making a spectroscope, eye model, color world, vibration and sound, have been accomplished. This ceminar-practicum as a non-formal teaching and learning gives opportunities for students to develop their creative potential, and enrich the theory and practice in Physics and Astronomy.
Keywords: physics, seminar-practice, education, experiments, students
Khimiya. 27, 825-830 (2018) Author(s): S. Savova:
Abstract.This article aims to present our work in the established educational community created in the school, the goals we have set ourselves, the activities carried out, the results obtained and the conclusions drawn. When comparing the results obtained, the test method and the questionnaire were used.
Keywords: basic learning, learning community, skills, cooperation, groups
Khimiya. 27, 831-835 (2018) Author(s): R. Rangelova, M. Mavrova:
Abstract.This paper describes several interdisciplinary lessons, competitions, games and home experiments. All of them were tested in practice with a good success.
Keywords: interdisciplinary lessons, games, home experiments
Khimiya. 27, 836-841 (2018) Author(s): M. Anastassova:
Abstract.Easy way for experimental determination of the Earth acceleration g is described.
Keywords: experimental task, Earth acceleration
Khimiya. 27, 842-849 (2018) Author(s): K. Katsarova, Z. Raykova:
Abstract.The aim of this paper is to present the results of educational research undertaken by students from Plovdiv School and associated with the construction of a model for the implementation of the teaching-research approach to studying the topic of mechanical oscillations and waves. This model includes certain components related to the formation of learning research tasks and the development of scenarios for the study of certain phenomena and specific applications of mechanical waves. It describes the expected results of such organized training and the concrete application of certain constructivist learning methods that are relevant to the research approach.
Keywords: inquiry-based science education, didactics of physics, mechanical oscillations and waves
Khimiya. 27, 850-854 (2018) Author(s): D. Uzunova, B. Velkovski, I. Simeonov, V. Shabanski, D. Kolev:
Abstract.A Club of robotics was established in the High School of Mathematics in Pleven. This initiative gives good results. The activities of the students in the Club are described in brief in the present article.
Keywords: robotics, beginners, school
Khimiya. 27, 855-863 (2018) Author(s): I. Hadjiali:
Abstract.The main goal of this report is to conduct a substantial analysis of some fundamental normative documents in the Secondary and university systems of education. A vector model of the professional competency of the biology teacher has been modeled on the grounds of this theoretical analysis. The concept of the discipline "The origin of life and theories of evolution" in the context of the standards of the biology teacher training at the University of Sofia is well described here. A piece of the curriculum in the form of topics and their descriptions is presented, as well.
Keywords: curriculum, evolution, professional training
Khimiya. 27, 864-870 (2018) Author(s): R. Georgiev, T. Dzimbova, A. Chapkanov:
Abstract.Bioactive peptides are protein fragments that have a positive impact on body functions and may ultimately influence health. Angiotensin-converting enzyme plays an important role in the control of arterial blood pressure. The main action of Angiotensin II is to maintain blood pressure and fluid balance in the body. It is obtained from the precursor under catalytic action of angiotensin-converting enzyme (ACE). In order to control (inhibit) the action of the ACE different inhibitors were proposed and some of them are already in use in the clinic. In the present investigation we design and docking studies of fife new potential ACE inhibitors. Three of the proposed analogues have a potential to be ACE inhibitors, as they bind to the enzyme stronger than His-Leu. The studied peptides may form as a basis for the design of new compounds and will be synthesized and biologically tested.
Keywords: angiotensin-converting enzyme, docking study, short peptides, ACE inhibitors
Khimiya. 27, 871-875 (2018) Author(s): K. T. Rustembekov, M. Stoev, A. A. Toibek:
Abstract.The binary zinc telluride with the s-elements were synthesized by solid-phase method from the tellurium (IV) oxides, zinc and sodium (potassium) carbonates. The types of symmetry, unit cell parameters, X-ray and pycnometric densities of the synthesized compounds were determined by X-ray analysis.
Keywords: binary zinc telluride, solid phase synthesis, X-ray
Khimiya. 27, 876-886 (2018) Author(s): A. Vasev, P. Lilov, G. Ivanova, Y. Marinov, A. Stoyanova, V. Mikli, A. Stoyanova - Ivanova:
Abstract.Conductive cuprate BSCCO (2212) ceramics, exhibiting superconductivity a low temperatures (80-100К) can find other applications as well, such as an additive in the zinc electrode of nickel-zinc batteries. Ni-Zn cells are a potential cheaper alternative to replace toxic nickel-cadmium batteries. The positive effect of cuprate ceramic additives has been previously demonstrated. The study, presented here is focused on the electrochemical characterization of Bi2Sr2CaCu2Ox (BSCCO 2212) nanocomposite conductive ceramics as an additive to the zinc electrode at 25oC and 50oC in an alkaline electrolyte containing KOH and Na3PO4. Three coin type electrodes (15mm in diameter) were investigated by Electrochemical Impedance Spectroscopy measurements by a Bio-logic SP-200 potentiostat in a wide frequency range (106 - 0.1 Hz). The tests were performed in a three-electrode electrochemical cell with different negative electrodes – one with "classic" conductive carbon additive, another with BSCCO 2212 additive, and the third without any additives (only ZnO). The obtained impedance spectra are compared and equivalent circuit models are proposed.
Keywords: electrochemical impedance, HTSC ceramics, BSCCO
Khimiya. 27, 887-896 (2018) Author(s): N. Dineva, I. Givechev, D. Tanev, D. Danalev:
Abstract.The calibration of method for determination of phthalates by means of GC/MS was done. The obtained working range for different phthalates is as following: DBP 58.8 – 1175,3 ppb; BBP 75,2 – 1504,6 ppb; DEHP 72,7 – 1454,2 ppb; DOP 59,1 – 1182,2 ppb; DINP 484,5 – 9690,3 ppb; DIDP 573,9 – 11477,0 ppb. Dicyclohexylphtalate (DICHP) was selected as an internal standard. Hexane is used as a solvent for preparation of standard solutions of phthalates.
Keywords: phthalates, GC/MS, LOD, LOQ, calibration
Khimiya. 27, 897-914 (2018) Author(s): M. Chochkova, B. Stoykova, I. Romanova, P. Petrova, I. Tsvetkova, H. Najdenski, L. Nikolaeva - Glomb, N. Nikolova, G. Ivanova, A. Chapkanov, T. Milkova, M. Sticha, I. Nemec:
Abstract.A series of 4-(substituted benzylidene-amino)-2,3-dimethyl-1-phenyl-3-pyrazoline-5-ones (3a-l) was obtained using sonochemical assisted reaction. The synthesized Schiff bases were evaluated for their antiviral, antibacterial, anticandida, DPPH scavenging and anti-tyrosinase activities in vitro. The antimicrobial screening results revealed that amongst the tested imines, compound 3l appeared to be а promising one (with a minimal inhibitory concentration 47 ug/ml). The most potent DPPH scavengers were azometines 3a and 3g. No significant inhibition on the monophenolase activity in vitro of mushroom tyrosinase was observed.
Keywords: 4-aminoantipyrine, Schiff bases, mushroom tyrosinase, antimicrobial activity, DPPH scavenging activity
Khimiya. 27, 915-921 (2018) Author(s): S.S. Fomanyuk, V.O. Smilyk, G.Y. Kolbasov, L.A. Rusetsky, T.A. Mirnaya:
Abstract.Colloidal solutions of ~2 nm CdSe nanoparticles have been obtained by electrosynthesis with simultaneous extraction into p-xylene. The effect of electrolyte composition on the structure of electrodeposited CdSe nanoparticles has been established, their absorption and photoluminescence spectra have been analyzed. Exciton absorption of light by synthesized CdSe nanoparticles splits into three bands, which is characteristically for the small CdSe nanoparticles. Photoluminescence excited at wavelengths corresponding to curve bending decreases in intensity within the 350 -550 nm region with a maximum of 430 nm. This fact indicates on the formation of small (~ 2 nm) of CdSe nanoparticles in the process of electrosynthesis as well. Studies have shown that by the proposed method of electrochemical synthesis it is possible to obtain nanoparticles that are promising for the creation of optical liquid–crystalline composites.
Keywords: electrosynthesis, CdSe nanoparticles, colloidal solution
Khimiya. 27, 922-934 (2018) Author(s): H.M.E. Madkour, O.E.A. Mostafa, E.A. El-Bardany, A.K. El-Ziaty, M. Nabil:
Abstract.The previously reported 6-amino-4-(4-chlorophenyl)-3-methyl-1,4-dihydropyrano[2, 3-c] pyrazole-5-carbonitrile 1 was prepared and utilized as a precursor for novel heterocycles such as Benzoxazinone4, Pyrazolopyranopyrimidines8,9,12,13and 20tetrazolopyrimidine15and triazolopyrimidine16with anticipated antimicrobial activity. The structural features of these novel heterocycles were characterized and confirmed by their spectral analysis as well as elemental analyses.
Keywords: pyrazolopyranooxazinones, pyranopyrimidines, triazolopyrimidines tetrazolopyrimidines and pyrazolopyranopyrimidinthion
Khimiya. 27, 935-939 (2018) Author(s): M. Filipova, D. Popova, S. Vezenkov:
Abstract.This work explores the clinical practice of venous thrombolysis in patients with ischemic stroke. Describes the experience gained and the results of the application of innovation in the rehabilitation of patients in neurological clinics. Venous thrombolysis is highly effective due to reduced hospital stay. The time to recover the motor deficit is limited to a minimum (sometimes to hours). The possibility of using the procedure in patients with severe co-morbidity expands the choice of recanalization.
Keywords: intravenous thrombolysis, stroke, physiotherapy